陈策实,43岁,中国科学院昆明动物研究所研究员,博士生导师。1994年7月,获得南开大学生命科学院微生物理学学士;1999年6月获得中科院上海生物工程研究中心和药物研究所博士学位。2006年1月至2009年12月,在美国纽约州阿尔巴尼市阿尔巴尼医学院细胞生物学和癌症研究中心任助理教授;2010年1月至2011年9月,提升为副教授;2011年9月至今担任中国科学院昆明动物研究所肿瘤生物学课题组长,研究员。2010年获得云南省“引进高端科技人才”,2011年获得中国科学院引进海外杰出人才(百人择优),2013年获得中国自然科学基金委“杰出青年”。已经在国际期刊上发表了50余篇论文,包括Nature Communications ,Cancer Research,Oncogene,Cell Death and Differentiation等。SCI-E被引用次数超过1480次。
 
Ceshi Chen,43, Professor of Kunming Institute of Zoology, the Chinese Academy of Sciences. Dr. Chen received his B.S. in Microbiology from NanKai University (1994) and Ph.D. from Shanghai Institute of MateriaMedica, Chinese Academy of Sciences (1999). Dr.Chen accepted his postdoctoral training at University of Virginia and Emory university from 1999 to 2005. Dr.Chen was appointed as Assistant professor (tenure track) at Albany Medical College, NY, USA in 2006, and was promoted to Associate professor in 2009. Dr. Chen served as Principal Investigate in Cancer Biology at Kunming Institute of Zoology since 2010.  Dr. Chen obtained as “High-Profile Scientist in Yunnan Province” in 2010,and “Outstanding oversea scientist of Chinese Academy of Sciences” in 2011. Dr. Chenwas rewarded as “Outstanding Young Scientist of National Science Foundation of China”  in 2013. Dr. Chen published more than 50 first-author or corresponding author papers/reviews in prestigious journals such as Nature Communications, Cancer Research, Oncogene, Cell Death & Differentiation,etc. SCI-E is cited more than 1480 times.
 
代表性5篇论文:
1. Junying Qin, Zhongmei Zhou, Wenlin Chen, Chunyan Wang, Hailin Zhang, GuangzheGe, Ming Shao, Dingyun You, Zhixiang Fan, Houjun Xia, Rong Liu, Ceshi Chen*, BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5, Nature Communications, 2015,doi:10.1038/ncomms9471 (IF 11.904)
2. Lin Jia, Zhongmei Zhou, Huichun Liang, Jing Wu, Peiguo Shi, Fubing Li, Zehua Wang, Chunyan Wang, Wenlin Chen, Hailin Zhang, Yang Wang, Rong Liu, Jing Feng*, Ceshi Chen*KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2, Oncogene, 2015 Jul 20. doi: 10.1038/onc.2015.263. [Epub ahead of print](IF 7.632)
3. Hou-Jun Xia, Bao-Li He, Chun-Yan Wang, Hai-Lin Zhang, Guang-ZheGe,  Yuan-XuZhang, Long-BaoLv, Jian-Lin Jiao, Ceshi Chen*, PTEN/PIK3CA genes are frequently mutated in spontaneous and MPA-accelerated DMBAinducedmammary tumours of tree shrews, Eur J Cancer, 2014, 50(18):3230-3242(IF: 5.624)
4. Dong Zhao, HanqiuZheng, Zhongmei Zhou, Ceshi Chen*, The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation, Cancer Research, 2010, 70(11): 4728-38 .
5. Yi Li, Zhongmei Zhou, Ceshi Chen*, WW domain containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis, Cell Death and Differentiation, 2008, 15: 1941-51 
 
 
 
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